Reaper: it has an automatible mix knob for every plugin. It seems retarded not to include that in a DAW. Folders make the workflow really nice. Routing is super flexible. You can even create feedback loops to assemble your own delay plugin.
Small footprint: you can install it onto a jump drive (usb stick) and take it with you everywhere.
I've used: Cubase, Sonar, Reaper







