[StrangeCat]

Here I'll answer this since no one answered my question.
It doesn't matter what sequencer you use what matters is your accoustics and your AD Converters. Do you have mixer that you are going back and to the sound card? Or are you just INB with Urs or UAD plugins, Powercore? How are you monitors and the room you hear mixes in?

All the sequencers out there will deliver now really. I think Nuendo has the most flexible routing but I have Cubase SX3 (I love what it can do with midi)

It is true in the bizz that most record studios use protools but that's doesn't mean that other sequencers can't do the same thing.

Protools is an expensive setup.

There really are alot of main Sequencers that can get the mixing job done:
Sonar
Cubase
Logic
Nuendo
and others i forget the names LOL